From your screenshot it appears that Google is your home page and that you don't get this message until you open New Tab.
Open IE, click the cogwheel top right and select Internet Options. On the General tab click the Tabs button. Set 'When a new tab is opened, open:' to either 'A blank page' or 'The new tab page' (ie, anything other than 'The new tab page with my news feed').
This is a workaround to stop the new tab page asking you to set up your news feed, not a cure. For that you need to configure your news feed. You may now be able to do that. If not, then try resetting IE to its defaults.