Basic check would be to look at the amount of extensions/Add-ons you have running.
extensions/Add-ons can cause slowdowns, especially multiple addons some of which can interact badly.
Incognito mode, by default, does not load extensions/Add-ons and your findings would suggest you have an issue with extensions/Add-ons
Try this ...
How to open Google Chrome with extensions disabled / turned off?
If it works you then need to remove
all your extensions/add-ins and one by one add each one back and see which one is he cause of the issue. it's a good idea to test the single Extension/Add-on at a time