Applications won't start; program file cannot be found

I'm having this issue where a software I download wont start because the program file cant be found. I went to the location of the file and clicked it but the application still wont start. the attachment is an example with adobe reader.

Does it happen with any other program/s? I've seen similar with infected computers where the .exe files wouldn't work.

so far only adobe reader and another program I had. Everything else seems to work fine.

Chazzy said:

so far only adobe reader and another program I had. Everything else seems to work fine.

Click to expand...

Uninstall both programs, reboot and re-install programs. Would also recommend Scan Disk and SFC.

http://www.thewindowsclub.com/disk-error-checking-windows-8

http://www.eightforums.com/tutorials/3047-sfc-scannow-command-run-windows-8-a.html

Rich