I think you're saying I should be good, though not guarantees.

I am not keen to disconnect and reconnect drives. In advance of loading Windows 8.1, I will backup everything. So even if the worst should happen, I should be okay.

Only default folders that I have on my other drives are "Documents" "Music" "Downloads" "Pictures" stuff like that. Everything else related to the operating system and software is located on my C drive.

I am thinking I should be okay.