I get bogged up with that Exclusive mode, but it may have been simply you were using the Tile app, no tile app will continue running if you switch to desktop, unless you drag the desktop down into the Tile so it is split. But usually your resources will favour which tile is live, if you have Desktop open in the live half of the tile, and Chrome/Yootoob on the smaller portion, it won't allow Chrome to use your audio engine. Yo could always try it, open Chrome, start a Yootoob vid, then right click up in the upper left, Desktop will pop up. drag that into the Yootoob windows until a horizontal bar appears.