Windows NTFS Compression and Native Boot VHD/ VHDX? Issues or Conflicts?

I am currently cleaning out my Windows 7 x64 Ultimate SP1 for a 2 step upgrade > Win 8 > Win 8.1 and then will convert it to VHD.

I have this \Windows\Installer folder that is taking a lot of space and seems to be unused mostly.

Eventually, I wish to clean it out/ delete it or major stuff inside it.

But, till then I was considering "compressing" option it as suggested here instead of delete/ remap right now.
disk space - Is it safe to delete from C:\Windows\Installer? - Super User
How can I to free up drive space from the Windows installer folder without killing Windows 8.1? - Super User

If I do this right now (during Win 7 > 8 > 8.1) I am wondering this will cause any issues creatingin or running the VHD?

I googled around for VHD and NTFS compression and did not find anything good or bad either way (with exception that Windows XP and VHD had some issues)
Be careful with VHDs and Windows XP Compressed Folders - Ben Armstrong - Site Home - MSDN Blogs