The wire resistance impacts the heat generated by the current flowing through the given wire, but does not impact the actual speed of electrical current.
What impacts the speed is the electromagnetic field generated by the electric charge or electricity. Electricity in vacuum travel at the speed of light; even in air, it travels close to light speed. That's because the electromagnetic field generated by electricity practically encounters no resistance. That's one of the reason why high voltage wires are not insulated.
The insulated wire introduces resistance to the electromagnetic field and since the electricity cannot travel faster than the electromagnetic field, the speed of electricity reduced to the electromagnetic field's speed. In computer, most if not all wiring is insulated. From the printed circuit board to the components, such as CPU, memory, video card, etc., all of them are insulated. Depending on the type insulation, the speed of electricity could be reduced by as much as 50%, or more.
The speed of light can be approximated as a foot per nanosecond; the 50% reduction is 6" per nanosecond, which is still plenty fast, when the insulation is accounted for. The CPU may have the longest internal circuit as 3", while the peripherals might be as far as over a foot away. Even if the peripherals would be as fast as the CPU, which they are not, they'd be about four times slower to respond than the CPU would, due to the insulation reduced speed of electricity.