eSata is just another attachment like USB. You have it either directly on your board or you can get a PCI card like for USB3. It attaches directly to the internal Sata channel. Although the specs are lower than the USB3 specs, in real life it is faster.What's eSATA btw? I mean are their different hard disks which are eSATA or what
I run it with an external enclosure like this one and you can put any Sata disk into it. Right now I have a SSD in it from where I run my virtual systems (5x Linux, Windows 8.1 and Android).